Fundamental studies of IgM anti-HBc radioimmunoassay kit.
نویسندگان
چکیده
منابع مشابه
Evaluation o f Anti-HBc IgM Estimation by Radioimmunoassay for Anti-HBc on Column Separateti IgM*
Tests for Igm antibody to hepatitis B core antigen (anti-HBc IgM) are useful diagnostic tools in the evaluation of patients with hepatitis B virus (HBV) infection. A m ethod is described for detecting anti-HBc IgM based on application of a commercially available radioimmunoassay for total antiHBc to column separated serum IgM and the technique is evaluated in patients with acute and chronic HBV...
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Hepatitis B core Antigen (or HBcAg) is the major component of the core particles of Hepatitis B virus (or HBV). Particles have a size of 27 nm and contain a circular double-stranded DNA molecule, a specific DNA-polymerase and HBcAg. HBcAg is composed of a single polypeptide of about 17 kD that is released upon disaggregation of the core particles; the antigen contains at least one immunological...
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The clinical value of an enzyme-linked immunosorbent assay (ELISA) for the detection of anti-HBc IgM was evaluated by testing 202 sera from acute viral hepatitis B (AVHB), hepatitis B (HB), chronic hepatitis (CAH), chronic liver disease (CLD), cirrhosis, primary hepatoma, HBsAg carrier, acute viral hepatitis A (AVHA), hepatitis A (HA), non-A, non-B (NANB) hepatitis and miscellaneous conditions ...
متن کاملQuantitative analysis of HBsAg, IgM anti-HBc and anti-HBc avidity in acute and chronic hepatitis B.
BACKGROUND AND OBJECTIVES We evaluated hepatitis B virus (HBV) serological markers by novel, quantitative immunoassays in order to study their behaviours and possible role in the various phases of HBV infection. STUDY DESIGN The quantitative determination of HBsAg and anti-HBc/IgM by chemiluminescent immunoassays (Abbott Architect) and the calculation of anti-HBc avidity index have been carri...
متن کاملSerological evidence of presence of HBsAg undetectable by conventional radioimmunoassay in anti-HBc positive blood donors.
Sera from two blood donors, one of whom was implicated in a case of post-transfusion hepatitis B, were found to be positive for anti-HBc and negative for HBsAg by conventional radioimmunoassay and were retested for HBsAg after concentration (pepsin digestion and polyethylene glycol precipitation). The presence of occult HBsAg was confirmed in both. These observations have implications for blood...
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ژورنال
عنوان ژورنال: RADIOISOTOPES
سال: 1986
ISSN: 1884-4111,0033-8303
DOI: 10.3769/radioisotopes.35.7_379